Intratumor heterogeneity and T cell exhaustion in primary CNS lymphoma
Sep 24, 2022
Cerebrospinal fluid flow cytometry distinguishes psychosis spectrum disorders from differential diagnoses
We performed basic CSF analysis and multi-dimensional flow cytometry of CSF and blood cells from 59 patients with primary psychotic disorders in comparison to inflammatory and non-inflammatory controls. We found an expansion of monocytes in the blood and CSF of psychosis patients. A machine learning model incorporating blood and CSF parameters differentated psychosis from non-inflammatory controls better than individual paramaters.
Aug 1, 2021
Neurological Manifestations of COVID-19 Feature T Cell Exhaustion and Dedifferentiated Monocytes in Cerebrospinal Fluid
We utilized single-cell sequencing and examined the immune cell profiles from the cerebrospinal fluid of Neuro-COVID patients and discovered an expansion of dedifferentiated monocytes and exhausted CD4+ T cells.
Jan 1, 2021
Leukocyte profiles in blood and CSF distinguish neurosarcoidosis from multiple sclerosis
Apr 1, 2020
Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis
Jan 1, 2020
Immune cell profiling of the cerebrospinal fluid provides pathogenetic insights into inflammatory neuropathies
Mar 1, 2019